Infectious Disease Genomics

Our teams are using genomics to better understand the origin of pathogen-based outbreaks and how infectious diseases spread.

  • Our Mycobacterium Reference Laboratory at Westmead is using genotyping to ensure tuberculosis (TB) has few places left to hide. The lab receives and analyses every TB culture from patients in NSW to help determine the genetic makeup of each individual case and see how many cases are potentially related. Results are logged in a database that informs public health investigations of possible transmission clusters.
  • We’re also working to better understand how bacteria like staphylococcus aureus (Staph) are becoming resistant to antibiotics. Our laboratories can sequence a whole bacterial or viral genome in one to two days. This information could lead to new ways of preventing life-threatening diseases and help inform the development of new and improved vaccines and antibiotics.
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